Taleatu, T. Akinwumi, Oluwatosin O. Oluyomi et al. (17 contributing authors)
Official complete volume edition for Journal of Humanities, Management and Social Sciences (JHUMASS), Volume 3 Number 1. Full text and all collected peer-reviewed articles are published and available in the attached issue compendium PDF.
Okanlawon, T. S., Ogundele et al. (10 contributing authors)
Leucaena leucocephala is a fast-growing leguminous plant this is used in the treatment of intestinal diseases and as birth control. This work was geared toward investigating the phytochemical attributes and the antimicrobial actions of methanol and distilled water crude extracts from the stem bark of Leucaena leucocephala in the ratio of 3:2 on nineteen bacterial species. The antimicrobial activity of the plant extract was done with the use of the agar diffusion technique in line with the National Committee for Clinical Laboratory Standards. The extract was located to be energetic against sixteen bacterial traces at a concentration of 35 mg/mL except for Bacillus anthracis, Clostridium sporogenes, and Pseudomonas fluorescens . The zones of inhibition exhibited by means of the extract towards the organisms ranged from 10.00 mm to 20.00 mm. The MIC exhibited by the extract ranged from 2.19 mg/ml to 8.75mg/ml while the MBC ranged from 4.38 mg/ml to 17.5 mg/ml. The effects of the extract on bacterial species were compared with the use of selected antibiotics such as streptomycin, and ampicillin. The phytochemical parts of the extract include tannins, glycosides, alkaloids, phenols, and terpenoids. Results from this research confirmed that the stem bark extract of Leucaena leucocephala exhibited antimicrobial activity against the selected bacteria and support the usefulness of this plant in folklore treatments.
Egwu, H. A., Yilwa et al. (14 contributing authors)
Hyptis suaveolens , an aromatic plant commonly called Daddoya-ta-daji in Hausa language, is traditionally used as medicine and food. It is used as stimulant, antirheumatic, carminative, against parasitic diseases, headaches, infection of the uterus, stomach, and skin diseases. It is found growing in both oil polluted and non-oil polluted environment. Oil pollution of land is a challenge due to the presence of heavy metals and volatile organic compounds which are harmful to crops and plants. This study investigated the phytoconstituents of the methanol leaf extract as well as antimicrobial activities of Hyptis suaveolens collected from polluted and unpolluted sites. Methanol leaf extracts of H. suaveolens were screened for crucial phytochemicals using standard methods. The in vitro antimicrobial activity was carried out using agar disc-diffusion method by Yahaya et al . (2018), using Mueller Hinton agar medium and potatoes dextrose agar in petri plates seeded with clinical isolates of Escherichia coli, Salmonella typhi, Shigella sp, Staphylococcus aureus (bacteria), Candida albicans and Aspergillus niger (fungi) respectively, and the zone of inhibition determined. The phytochemical results showed that methanol extract of both the polluted and non-polluted H. suaveolens leaves exhibited the presence of some number of bioactive compounds. Gas Chromatography–Mass Spectrometry (GC-MS) of polluted and non-polluted leaves of H. suaveolens identified 13 and 21 compounds, respectively such as Octadec-9-enoic acid, 2-Ethylacridine, Methyl ester, Tetracyclo [4.4.1.1(7,10).0(2,5)] dodec-3-en-11-ol, 1,2-Diphenyl-1-isocyanoethane and 7-Isopropyl-1, 1, 4a-trimethy l-1,2,3,4,4a,9,10,10 aocta -hydrophenanthrene. These chemical compounds are considered biologically and pharmacologically important. The results from assessment of the antimicrobial potential of H. suaveolens (L.) on pathogenic microorganisms showed that the pathogenic microorganisms revealed inhibition zones ranging from 6 to 18 mm. This data indicates that the unpolluted methanol extract of H. Suaveolens exhibits a higher bioactive potential compared to the extract derived from polluted leaves. This disparity suggests that oil pollution may have a detrimental impact on the biochemical properties of the plant.
